CONCH

Maintainer: MahmoodLab

Total Score

50

Last updated 5/15/2024

🛠️

PropertyValue
Run this modelRun on HuggingFace
API specView on HuggingFace
Github linkNo Github link provided
Paper linkNo paper link provided

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Model overview

CONCH (CONtrastive learning from Captions for Histopathology) is a vision language foundation model for histopathology developed by MahmoodLab. Compared to other vision language models, CONCH demonstrates state-of-the-art performance across 14 computational pathology tasks, ranging from image classification to text-to-image retrieval and tissue segmentation. Unlike models trained on large public histology slide collections, CONCH avoids potential data contamination, making it suitable for building and evaluating pathology AI models with minimal risk.

Model inputs and outputs

CONCH is a versatile model that can handle both histopathology images and text. It takes in a variety of inputs, including:

Inputs

  • Histopathology images: The model can process images from different staining techniques, such as H&E, IHC, and special stains.
  • Text: The model can handle textual inputs, such as captions or clinical notes, that are relevant to the histopathology images.

Outputs

  • Image classification: CONCH can classify histopathology images into different categories, such as disease types or tissue types.
  • Text-to-image retrieval: The model can retrieve relevant histopathology images based on textual queries.
  • Image-to-text retrieval: Conversely, the model can generate relevant text descriptions for a given histopathology image.
  • Tissue segmentation: CONCH can segment different tissue regions within a histopathology image.

Capabilities

CONCH is a powerful model that can be leveraged for a wide range of computational pathology tasks. Its pretraining on a large histopathology-specific dataset, combined with its state-of-the-art performance, makes it a valuable tool for researchers and clinicians working in the field of digital pathology.

What can I use it for?

Researchers and clinicians in the field of computational pathology can use CONCH for a variety of applications, such as:

  • Developing and evaluating pathology AI models: Since CONCH was not trained on large public histology slide collections, it can be used to build and evaluate pathology AI models without the risk of data contamination.
  • Automating image analysis and reporting: The model's capabilities in image classification, tissue segmentation, and text generation can be leveraged to automate various aspects of histopathology analysis and reporting.
  • Facilitating research and collaboration: By providing a strong foundation for computational pathology tasks, CONCH can help accelerate research and enable more effective collaboration between researchers and clinicians.

Things to try

One interesting aspect of CONCH is its ability to process non-H&E stained images, such as IHCs and special stains. Researchers can explore how the model's performance compares across different staining techniques and investigate its versatility in handling a variety of histopathology imaging modalities.

Additionally, the model's text-to-image and image-to-text retrieval capabilities can be leveraged to explore the relationship between histopathology images and their associated textual descriptions, potentially leading to new insights and discoveries in the field of digital pathology.

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